The Ultimate Guide to CBGa: Mother of All Cannabinoids

Cannabinoids are the chemical components found in the cannabis plant along with the other 100+ compounds. They are responsible for managing an array of functions and cannabis is widely known for having therapeutic effects. Did you know there are 400 and above cannabis compounds and hundreds of them are termed as cannabinoids? Yes, you heard it right, the cannabis plant is composed of several cannabinoids. Out of which only a few are known to the human race. The notorious psychoactive THC and non-psychoactive CBD. Both these compounds have the ability to treat a wide range of medical conditions like cancer, PTSD, glaucoma, epilepsy, Alzheimer’s disease, HIV/AIDS, etc.

Besides the most well-known compounds, there is another that holds an equally mysterious position in the cannabis world – Cannabigerolic acid (CBGa). Interestingly, no other cannabis compound can exist without the benign presence of CBGa. While CBD relieves individuals from paranoia and anxiety and THC creates a perfect relaxing environment. In this post, we will solely focus on CBGa. So, let’s get started.

What is cannabigerol acid (CBGa)?

CBGa is also termed as the mother of all phytocannabinoids and for a reason. The most evident reason is that CBGa is a precursor of all the other cannabinoids present in the marijuana plant. Precisely why other compounds will be non-existent without CBGa. It is formed when two organic compounds (olivetolic acid and geranyl pyrophosphate) present in the cannabis plant combine with each other. Not only this but CBGa also acts as a building block in the formation of cannabinoids like CBG, THCa, CBDa, and CBCa.

Cannabigerol acid is produced with the help of trichomes in the marijuana plants and its function is to protect the plant by directing the energy in the upward direction. This process also targets plant cell necrosis which in turn is good for natural leaf pruning. So, it wouldn’t be wrong to say that CBGa is the spine of the cannabis plant and it always stays at the top of the chemical chain reaction. The same chemical reaction that leads to the formation of CBD, THC, CBC, and CBG. However, CBGa eventually gets converted into CBG. But you might be wondering how CBG and CBGa are different. Let’s discuss it below in this post.

What is the difference between CBG and CBGa?

For those who don’t know cannabinoids come in two different forms. One form is acidic and non-acidic. So, you have to keep in mind that both CBD and THC are non-acidic forms. Especially considering the fact that they are excessively used for the treatment of medical conditions. While CBDa and THCa are the acidic forms. So if we look at CBG and CBGa, they both also fall in the same category.

Often acidic forms of cannabinoids associate themselves with raw cannabis and non-acidic with the heated form of cannabis. Now that you know all about the acidic and non-acidic nature of the cannabis plant. Let us dive right into the nitty and gritty of CNG and CBGa formation. Imagine heating CBGa molecules in a flask. What will you get? You don’t have to think hard. It’s simple, tiny molecules of CBG which are also responsible for producing the rest of the cannabinoids.

Whereas CBGa formation occurs when geranyl acid and olivetolic acid combine as I have mentioned earlier in this post. In addition to this, both CBG and CBGa work in tandem with each other to form the two main compounds of the cannabis plant – CBD and THC. Interestingly, the acidic form of CBG is similar to the stem cells in the human body. This means that this component is an integral part of the cannabis family.

What are the benefits of CBGa?

Unfortunately, there is very little research on CBGa. Unlike CBD and THC, these components have more research than the aforementioned compound. But we do have a few studies that talk about the possible benefits of cannabigerol acid.

CBGa can help combat diabetes

The study on CBGa suggests that diabetes can be the leading cause of death for patients dealing with cardiovascular diseases. This is where the role of CBGa comes in. According to this study, CBGa may inhibit ALR2 enzymes and eventually reduce oxidative stress. Which in turn is a good sign for patients suffering from cardiovascular disease?

In the near future, CBGa might kill colon cancer cells 

A 2018 study, revealed that CBGa has cytotoxic effects. This means that it can kill colon cancer cells and also reduce the growth of cancer cells. However, further research on this topic will definitely open doors to new revelations. For now, scientists are quite encouraged and positive that CBGa has the potential to prevent the growth of polyps and cancer cells.

CBGa may also help patients suffering from metabolic disorders

Another 2019 study reported that peroxisome proliferator-activated receptors (PPARs) are necessary for the regulation of metabolism. And CBGa might help in the reduction of lipid accumulation. This also means that this component definitely has a significant role to play in the near future.

The final thought 

If you haven’t heard about CBGa. This is probably the right time to learn about this infamous compound of the cannabis plant. There’s a lot that the future has in store for CBGa but unfortunately, we still have to wait for the scientific minds to uncover its full potential. Till then you can familiarize yourself with the other components of the cannabis plant. However, don’t forget that if you are using cannabis products that contain THC, you will need a medical marijuana card in California because unsupervised guidance can lead to negative consequences.

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Author: Guest Contributor

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